Overview
Research Interests
We apply a variety of biophysical chemistry techniques to understand the function of partially disordered proteins and to define the features of protein-RNA interactions. We are primarily Nuclear Magnetic Renonance (NMR) spectroscopists, but feel strongly that understanding biological chemistry requires the application of diverse techniques. NMR studies of protein dynamics combined with computational and theoretical studies of the coupling between nuclear spin relaxation and molecular motion provide a complete picture of protein structure. Emphasis is placed on biophysical studies of macromolecular interactions involving partially disordered proteins and/or protein-RNA interactions in order to build the connection with function. We wish to understand the functional implications of protein dynamics and disorder in protein mediated signaling and other biological events.
For specific projects, please click the Research link to the left.
Seeking Graduate Students for Fall 2009
Congratulations to our incoming class of graduate students!
The Showalter laboratory is seeking highly motivated graduate students looking for interdisciplinary training in biophysical chemistry. If you are interested in our lab, please feel free to
E-mail Dr. Showalter for more information.
For more details on available projects and other considerations, please follow the Research or Positions Available links.
Seeking Undergraduate Students
Outstanding undergraduates at Penn State are always welcome in our laboratory. If you are looking for an undergraduate research position and the research we have introduced here sounds like a good fit for you, please E-mail Dr. Showalter for more information.